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management differential hematology rheumatology abnormalities amiodarone apml breathing bronchiectasis cryofibrinogenemia differentiation encephalopathy induced lung neurology oncology patterns posterior pres reversible
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... anterior/posterior MSK ... ), liver (pain/abnormal
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms ... circulation: MCA ACA ... Constipation, Seizures, Stroke ... epilepticus Treatment ... underlying cause • Treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... 500 mg QD until normal
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Mounier-Kuhn syndrome ... parenchyma Diagnosis ... - BAR >1.0 is abnormal ... mycobacteria Treatment
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Presentation: Systemic Symptoms ... Palpable purpura: Strong ... • Progressive symptoms ... fluid (CSF) is abnormal
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Albuminuria, nephrotic syndrome ... meningovascular disease, or stroke ... ulcerated • MSK ... infected without symptoms ... Syphilis #stages #diagnosis
Abnormalities in Rate and Rhythm of Breathing Normal The respiratory rate is about 14—20 per min
Cheyne-Stokes Breathing ... hyperventilation syndrome—a ... Breathing #Patterns #Pulmonary ... Abnormalities #Abnormal ... #Diagnosis #PhysicalExam
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... Cryofibrinogenemia Symptoms ... Related conditions: Stroke ... thrombophlebitis, pulmonary ... Antiphospholipid syndrome
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... gradually with symptoms ... Improvement in symptoms ... macrophages Treatment
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