14 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ) Clinical Guidelines ... #Acute #Chronic ... Failure #Cirrhosis #Hepatology ... #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... #comparison #table ... #rheumatology # ... diagnosis #management
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Maternal Support - Critical
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: • Acute ... erythematosus (ACLE ... Differential Diagnosis ... Pleural effusions • Acute
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Highly variable clinical ... subclinical disease to acute ... Anti-LKM & Anti-ALC ... Hepatitis (eg Viral) Management ... #Management #Hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
: • Clinical Suspicion ... Confirmatory test ↑Se ... D/c all heparin ... non-heparin A/C if clinical ... #Hematology #HemeOnc
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
narrowing) • Ultrasound ... Diagnosis: CLINICAL ... DIAGNOSIS based ... ideally limit for acute ... #management #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Acute ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
5-Oxoprolinuria
What is it:
 • Aka pyroglutamic acidosis, Intermediate in γ-glutamyl cycle
 • Amino acid transport and
• Concomitant acute ... high index of clinical ... turnaround) • le ... screen Treatment (all ... #management #treatment