31 results
Ice-pack Test for Myasthenia Gravis - Likelihood Ratio (LR) +24 / -0.16
Ice pack's can be used
Ice-pack Test for ... Myasthenia Gravis ... effectively increasing ACh ... #Myasthenia #Gravis ... #physicalexam #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Bedside: ice pack test ... /Edrophonium test ... immunologic assay - MuSK ... Gravis #diagnosis #management ... #neurology
Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Action Source Text ... /critical-care-nephrology ... Action #Location #Nephrology ... #Pathophysiology ... #Pharmacology
Ocular Myasthenia Gravis on Physical Exam

A 41yo female was referred by her neurologist for double vision.
suspected and anti-ACh ... and the ice pack test ... include a Tensilon test ... tumor, and always ask ... ophthalmology #neurology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
antibodies - MuSK-positive ... • All patients ... be performed in all ... Gravis #diagnosis #management ... #neurology #treatment
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
tremor, ataxia, asthenia ... • Neurologic ... diplopia, ataxia, asthenia ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Central Nervous System Pharmacology - Somatic and Autonomic Receptors
Somatic
 • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
Nervous System Pharmacology ... the levels of Ach ... Parasympathetic “Rest ... Amy Chung, MD, MSc ... Autonomic #Receptors #Pharmacology
Acute Treatment of Migraine
Mild Attacks: NSAIDs, Simple Analgesics
Moderate/Severe Attacks: Triptans, Ditans, Gepants, Ergots
Non-pharmacologic Treatment: Neuromodulation, Rest,
Gepants, Ergots Non-pharmacologic ... Neuromodulation, Rest ... acute #treatment #management ... #neurology
Migraine - Preventative Treatments

 • Anticonvulsants: *Topiramate, *Sodium valproate, Gabapentin, Pregabalin
 • Antidepressants: Amitriptyline, Venlafaxine, Duloxetine,
Beta-blockers, ACE ... Preventative #Treatment #management ... prophylaxis #prevention #pharmacology ... #neurology
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Epidemiology: • Rest ... younger than other ACS ... Pathophysiology: ... perform provocative tests ... cardiology #diagnosis #management