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diagnosis anthracycline cardiology cardiotoxicity chemotherapy differential diuresis encephalopathy excretion hematology her2 immune inflammatory iris leukostasis lysis medications nephrology neurology oncology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome ... irrigation • Management ... Inhibitors of Na+K+2Cl ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
• Triggers: Diuretics ... have fever - ACS ... limb ischemia, bowel ... organ damage • Treatment ... TLS #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
(PRES) Overview ... circulation: MCA ACA ... Medication/Drug toxicity ... epilepticus Treatment ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... - Overview of IRIS ... serositis peritonitis, bowel ... Drug reaction/ART toxicity ... Differential #Diagnosis #Management
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... ) and initiate treatment ... antagonist (MRA) plus diuretic ... cardiology #oncology #pharmacology ... #toxicity #chemotherapy
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