21 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... not required in all ... When do you do a BM ... #Differential #Diagnosis ... #hematology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome - Causes ... hyperleukocytosis (AML ... - MH/CCF/CWRU EM ... #Differential #Diagnosis ... #Treatment #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... : Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... symptoms, unexplained hematologic ... to 50% of PTLD cases ... Disorders #oncology #diagnosis ... #management #transplant
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
scleroderma) - Anti-Scl ... seen in 30—70% of cases ... + 90% • Anti-GBM ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis ... #management #treatment ... #summary #rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... Step 3: All patients ... including liver and hematologic ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Antithrombin Ill • Ultrasound ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
thiazidic, PPI, ACE ... Discontinuation of causal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Parvovirus B19 - EBV ... Anemia #oncology #hematology ... #diagnosis #management