7 results
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
: weight gain, lung ... peripheral edema, ascites ... HFrEF may lack lung ... bilateral pleural effusions ... #pharmacology #
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
1 — Treat the lungs ... edema - Large effusion ... (no B-lines on ultrasound ... Revascularization, treatment ... NSAlDs, ACE-inhibitors
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... importantly, bedside ultrasound ... with presence of pulmonary ... icu #clinical #pharmacology
Abdominal Compartment Syndrome & Intrabdominal Pressure Measurement
APP (Abdominal Perfusion Pressure) = MAP (Mean Arterial Pressure) -
Perfusion Pressure ... CO) and impedes lung ... Chronic (due to long ... standing ascites ... after previous treatment
Stage III - Alveolar edema
This stage is characterized by continued fluid leakage into the interstitium, which
space (pleural effusion ... position Obstructive lung ... The following signs ... After treatment ... #Clinical #Radiology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
CT abdomen if abdominal ... interventional radiology ... (~20 %) and APL ... renal failure, pulmonary ... , SOB, pleural effusions
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
) and initiate treatment ... after 4 cycles for all ... of therapy • Long-term ... dose, continuous infusion ... #oncology #pharmacology