12 results
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
at anytime if toxicity ... Theophylline - For i/v infusion ... - Continuous infusion ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
Local Anaesthetic Toxicity ... Signs of severe toxicity ... tachyarrhythmias may all ... anaesthetic (remember infusion ... Diagnosis #Management #Workup
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Propofol #Related #Infusion ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
decreased renal perfusion ... hormones that act ... to improve the perfusion ... Muner Mohamed @MunerMohamed1 ... renal #nephrology #pharmacology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
exudative pleural effusions ... of lipid-laden 'foamy ... • Presence of foamy ... cellular counts • Foamy ... diagnosis #management #Toxicology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
its Chloride (Cl ... ECF and ICF both work ... blood flow and perfusion ... #foamed #criticalcare ... diagnosis #treatment #pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... importantly, bedside ultrasound ... Adequate perfusion ... treatment #table #foamed ... icu #clinical #pharmacology
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
reservoir bag and APL ... rate, rhythm, perfusion ... local anaesthetic toxicity ... Diagnosis #Management #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
reservoir bag and APL ... rate, rhythm, perfusion ... local anaesthetic toxicity ... Diagnosis #Management #Workup
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
reservoir bag and APL ... rate, rhythm, perfusion ... Local anaesthetic toxicity ... Diagnosis #Management #Workup