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management oncology barre differential guillain neurology rheumatology algorithm anemia aplastic apml cryofibrinogenemia differentiation emergencies enzymes erythematosus gap gbs guillainbarre hepatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cold insoluble globulin ... Infections including coronavirus ... disease 2019 (COVID ... Antiphospholipid syndrome ... hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
(MDS) (normal or ... aplastic anemia Treatment ... antithymocyte globulin ... Anemia #oncology #hematology ... #diagnosis #management
Orthopedic Emergencies Compartment Syndrome • An increase in compartment pressure to the point where tissue perfusion is
- Remove all ... presence of fat globules ... in the lung parenchyma ... • Diagnosis: ... #management #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... cell types are abnormal ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... 500 mg QD until normal ... #management #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
box indicates all ... presence of metabolic syndrome ... Areas of diagnostic ... mellitus; USS, ultrasound ... #Algorithm #Hepatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
like illnesses, COVID ... Guillain-Barre Diagnosis ... CSF PROTEIN - NORMAL ... #diagnosis #management ... #treatment #neurology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... ovarian tumors, lung ... chain assay • An abnormal ... #differential #diagnosis ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
erythematosus (ACLE ... Differential Diagnosis ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... Erythematosus #Diagnosis
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... and cauda equina TREATMENT ... Intravenous Immune globulin ... Guillain #Barre #Syndrome
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