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management oncology gastroenterology rheumatology algorithm differential chronic cirrhosis hepatopulmonary leukemia liver abnormal aclf activation acute aih anemia aplastic apml autoimmune
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... have fever - ACS ... #TLS #diagnosis ... #management #hematology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Liver Failure (ACLF ... months without treatment ... Brain Failure Lung ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary Diagnosis: • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... Treatment: • Global ... Gastroenterology and Hepatology ... Irritable #Bowel #Syndrome ... gastroenterology #treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... When present, symptoms ... transformation into AML ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... : >3 symptoms, or ... #management #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... on radioactive lung ... resolution of symptoms ... #treatment #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... HLH signs and symptoms ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... box indicates all ... presence of metabolic syndrome ... mellitus; USS, ultrasound ... Abnormal #Algorithm #Hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
- Symptoms of ... , AIH diagnosis ... Anti-LKM & Anti-ALC ... regarding need for treatment ... #Management #Hepatology
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