15 results
Jaw Clonus on Physical Exam

A 24-year-old man presented with progressive dysphagia, dysarthria, and weakness in his
clonus and muscle fasciculations ... consistent with a diagnosis ... #PhysicalExam #Clinical ... #Video #ALS #Neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... Common Symptoms ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... : >3 symptoms, or ... initiation • Differential ... unless severe APLS ... #diagnosis #management
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... heavy metals), Critical ... Syndrome, Myasthenia Gravis ... Weakness #Causes #differential ... #diagnosis #neurology
Diplopia - Double Vision - Differential Diagnosis Algorithm
Clinical Pearls:
 • Diplopia is almost always binocular.
 •
Double Vision - Differential ... Clinical Pearls ... • Neurologic ... symptoms suggest ... a mass as the cause
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... myasthenia Diagnosis ... #diagnosis #management ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... Diagnosis Framework ... should be based on clinical ... CNS #Infections #differential ... #diagnosis #AIDS
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... high index of clinical ... is required for diagnosis ... Autoimmune (SLE/APLS ... #Endocarditis #comparison
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... Symptom | Diagnosis ... • Muscular or neurologic ... Other - ALS, Dementia ... #Diagnosis #Management
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Coltivirus Symptoms ... • Common clinical ... influenzae Symptoms ... /l is regarded as ... #diagnosis #neurology