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hematology leukemia management chronic hodgkins lymphocytic lymphoma classification differential differentiation gammopathy hemeonc mds mgus myelodysplasia myelodysplastic nonhodgkins plasmacytoma significance solitary
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL Symptoms: ... ) CLL Symptoms: ... transformation of the CLL ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
typically of B-cell ... Reed Sternberg cell ... based on: - Cell ... type (B cell, T ... #oncology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... Transformation to large cell ... fludarabine) 3) Monoclonal ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Release from blast cells ... • Induce blast cell ... : >3 symptoms, or ... Differentiation #Syndrome #APML ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
constitutional symptoms ... marrow plasma cells ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Solitary Cell Plasmacytoma ... • Plasma cell neoplasms ... MM, the plasma cell ... #Solitary #Cell ... #Diagnosis #Workup
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