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hematology management chronic differential hemeonc hodgkins lymphocytic lymphoma cell classification druginduced emergencies gammopathy gap globulin lupus mds mgus myelodysplasia myelodysplastic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... ALL Symptoms: ... ) CLL Symptoms: ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Diagnosis: • ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... fludarabine) 3) Monoclonal ... uw_IMresidency #CLL ... #oncology #hematology ... #hemeonc #diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... Differential Diagnosis ... #NonHodgkins #comparison ... #oncology #diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... constitutional symptoms ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... Constitutional symptoms ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... Usually myeloid leukemias ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Causes of Monoclonal ... leukemia • Solitary ... : Lymphoma, Leukemia ... #differential #diagnosis
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