12 results
Thrombocytopenia 
Work up, differential diagnosis and management.

Satyendra Dhar MD, @DharSaty

#thrombocytopenia #platelets #ITP #DIC
Thrombocytopenia ... Work up, differential ... diagnosis and management ... #platelets #ITP ... #DIC
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential ... Diagnosis and Workup ... #Differential # ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... • Platelet defects ... : - Thrombocytopenia ... Vasculopathy #Purpura #Differential
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
for Causes of Thrombocytopenia ... Disorders (DIC, ... Mnemonic #Acronym #Thrombocytopenia ... #Differential # ... Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
: • Platelet count ... - Platelet rich ... Treat primary cause ... #treatment #management ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
with or without platelet ... Schistocytes, thrombocytopenia ... - DIC, TTP, HELLP ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemostasis: - Thrombocytopenia ... - Abnormal platelet ... fulminans - DIC ... deficiency Work
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... and decreased platelet ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... count (thrombocytopenia ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... Causes purpura & ... severe thrombocytopenia ... Transfusions #diagnosis #management ... #hematology #reactions