22 results
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
cough, SOB • Chronic ... 45yo, F; Hx of asthma ... SOB, sinusitis, wheezing ... Weeks) - Hx of asthma ... , CF; Chronic cough
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Effusions - Rare Peripheral ... mechanical ventilation Chronic ... tobacco hx, >60% asthma ... Constitutional Symptoms - Peripheral ... edema" - Common Peripheral
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... q4 weeks • Peripheral ... q8 weeks • Peripheral ... #asthma #Biologic
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
therapies for Asthma ... , Asthma-COPD Overlap ... , and ACO initially ... analysis with eosinophil ... ACO = asthma-COPD
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... Primary Eosinophilia ... Secondary Eosinophilia ... histiocytosis • Allergic: Asthma ... insufficiency, Chronic
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... FOR TESTING: • Peripheral ... blood eosinophilia ... specific symptoms • Eosinophilia ... common causes are asthma
Causes of Chronic Pediatric Cough - Differential Diagnosis Algorithm
Poor Growth
 - Non-Specific CXR
Causes of Chronic ... Immunodeficiency • Chronic ... Poorly Controlled Asthma ... /URTl: • Asthma ... Algorithm #Causes #Peds
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... DRESS - AIN - Eosinophilic ... Dermatitis - Asthma ... Hypereosinophilic Syndrome - Chronic ... Eosinophilic Leukemia
The infant with tachypnea or wheeze - Clinical Conditions to Consider
 - Bronchiolitis 
 - Pneumonia
Transient early wheezing ... - Non-atopic wheezing ... infection - Atopic asthma ... — recurrent wheezing ... #Diagnosis #Peds
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm
CXR Abnormal:
 • Pulmonary Sequestration
 • Congenital Adenoid Cystic
Causes of Pediatric Wheezing ... Beta-Agonist: • Asthma ... Structural Anomaly #Wheezing ... Algorithm #Causes #Peds