21 results
Eosinophilic Pneumonia
When to suspect Eosinophilic Pneumonia? Non-resolving pneumonia + BAL > 25% eosinophils + excluded more
Effusions - Rare Peripheral ... tobacco hx, >60% asthma ... Consolidations AKA "inverse pulmonary ... edema" - Common Peripheral ... Pneumonia #diagnosis #pulmonary
Biologic therapy for eosinophilic asthma 
• Mepolizumab (Nucala) 
  • Anti-lL-5, 100 mg SQ q4
asthma • Mepolizumab ... q4 weeks • Peripheral ... q4 weeks • Peripheral ... #asthma #Biologic ... #pharmacology #pulmonary
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
45yo, F; Hx of asthma ... SOB, sinusitis, wheezing ... Weeks) - Hx of asthma ... food hx; Fever, wheezing ... Lung #Diseases #pulmonary
Causes of Pediatric Wheezing - Differential Diagnosis Algorithm
CXR Abnormal:
 • Pulmonary Sequestration
 • Congenital Adenoid Cystic
Causes of Pediatric Wheezing ... Abnormal: • Pulmonary ... Beta-Agonist: • Asthma ... Algorithm #Causes #Peds ... #Pediatrics #Pulmonary
First-line therapies for Asthma, Asthma-COPD Overlap and COPD

The diagnosis of COPD, asthma, and ACO initially requires
therapies for Asthma ... , Asthma-COPD Overlap ... , and ACO initially ... analysis with eosinophil ... ACO = asthma-COPD
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... FOR TESTING: • Peripheral ... blood eosinophilia ... specific symptoms • Eosinophilia ... common causes are asthma
The infant with tachypnea or wheeze - Clinical Conditions to Consider
 - Bronchiolitis 
 - Pneumonia
Transient early wheezing ... - Non-atopic wheezing ... infection - Atopic asthma ... — recurrent wheezing ... #Diagnosis #Peds
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
destructive sinusitis, pulmonary ... lung disease • Eosinophilic ... polyangiitis - Asthma ... . eosinophilia.
Severe Asthma Exacerbation
Signs of a Severe Asthma Exacerbation:
 • Vitals: ↑HR ↑RR ↓SpO2
 • High work
Severe Asthma Exacerbation ... Signs of a Severe Asthma ... sentences • Diffuse wheezing ... Ventilation in Asthma ... #CriticalCare #pulmonary
An Algorithm for the Diagnosis of Wheezing and Stridor

Stridor: Louder, constant-pitch sound over central airways
Wheezing: Musical
the Diagnosis of Wheezing ... central airways Wheezing ... Bronchoconstriction: Asthma ... Peribronchial pulmonary ... diagnosis #algorithm #pulmonary