7 results
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
ACEI Antihypertensive ... the following ACEIs ... Monitor BP, potassium ... #Dosing #Conversion ... #Pharmacology #
Angiotensin Receptor Blockers 
Recommended Dose Conversions 

Valsartan 
Irbesartan 
Losartan 
Olmesartan 
Telmisartan 
Candesartan 
Azilsartan 
Eprosartan 

A few
cough compared to ACEI's ... As a refresher, ... for increased potassium ... #Table #Dosing ... #Pharmacology #Dose
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... • NSAIDs • ACE ... • Recent IV potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... • NSAIDs • ACE ... • Recent IV potassium ... #high #nephrology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... • Mutism Pathophysiology ... pontine lesion • Roving ... Glasgow Coma Scale (GCS ... #PhysicalExam #neurology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
hypokalemic salt-losing ... Hypokalemia (renal potassium ... ratio 0.5%) Differential ... Supplement: • Potassium ... #management #pathophysiology