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diagnosis nephrology causes hyperkalemia high algorithm aniongap chloride comatose druginduced gitelman hypochloremia hypokalemia management medications metabolic nongap physicalexam syndrome
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... • NSAIDs • ACE ... - Metabolic acidosis ... #high #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Gap Metabolic Acidosis ... Potassium-sparing ... ACE-Is and ARBs ... #differential # ... diagnosis #causes #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... • NSAIDs • ACE ... - Metabolic acidosis ... #high #nephrology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Hypochloremia - Differential ... Hypotension • AMS ... cause metabolic acidosis ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
hypokalemic salt-losing ... ratio 0.5%) Differential ... Renal tubular acidosis ... Supplement: • Potassium ... #management #pathophysiology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... • Mutism Pathophysiology ... pontine lesion • Roving ... Glasgow Coma Scale (GCS ... #PhysicalExam #neurology
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