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management potassium anesthesia causes checklist nephrology workup high intraoperative neurology pathophysiology syndrome binder bradycardia cardiacarrest cardiology druginduced encephalopathy gitelman gravis
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... #differential # ... diagnosis #pathophysiology ... #pharmacology #
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
INDICATION: Treatment ... oral suspension DOSING ... from other oral drugs ... this from other drugs ... #Pharmacology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... Clenching of fist during ... reactions Common Drugs ... • NSAIDs • ACE
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Diagnosis Framework ... Clenching of fist during ... reactions Common Drugs ... • NSAIDs • ACE
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis Overview ... life-threatening Differential ... myasthenia Diagnosis ... precipitated by: Drugs ... Myasthenia #Gravis #diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Syndrome (PRES) Overview ... Blood transfusion, Hypercalcemia ... Reversible course Differential ... abnormality, Medication/Drug ... epilepticus Treatment
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... anaphylaxis (→ 3-1) Drug ... #Hyperthermia #Differential ... #Causes #Anesthesiology ... Anesthesia #Checklist #Diagnosis
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
Hypovolaemia Hypo/hyperkalaemia ... : Vagal tone Drug ... CardiacArrest #Checklist #Differential ... #Anesthesiology ... Intraoperative #Checklist #Diagnosis
Intraoperative Bradycardia - Guidelines for Crises in Anaesthesia Bradycardia in theatre should not be treated as
not be treated as ... remember to tailor treatment ... myocardial infarction, hyperkalaemia ... #Bradycardia #Anesthesiology ... Intraoperative #Checklist #Diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome Overview ... hypokalemic salt-losing ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... Gitelman #Syndrome #diagnosis
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