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A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
antipsychotics, oxybutynin, ACh ... - Cholinergic: ACh ... antihistamines #Diagnosis
Ice-pack Test for Myasthenia Gravis - Likelihood Ratio (LR) +24 / -0.16
Ice pack's can be used
effectively increasing ACh ... physicalexam #neurology #diagnosis
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ab to AChR blocks ... myasthenia Diagnosis ... Labs: - AchR antibodies ... Myasthenia #Gravis #diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... #pharmacology #diagnosis
Central Nervous System Pharmacology - Somatic and Autonomic Receptors
Somatic
 • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
blocks action AchE ... the levels of Ach ... and Digest” - Ach ... Fight or Flight” - Ach ... Adrenal Medulla - Ach
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
Primary varicocele ache ... Symptoms #Urology #Diagnosis
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Antagonism - Block ACh ... #pharmacology #diagnosis
Diagnostic Criteria for Systemic Lupus Erythematosus - ACR and SLICC Criteria

#Diagnosis #Rheumatology #SLE #Lupus #Erythematosus #Criteria
Diagnostic Criteria ... Erythematosus - ACR ... SLICC Criteria #Diagnosis ... Erythematosus #Criteria #ACR
Drug-Induced Urinary Retention

Drug-induced urinary retention is very common and can be caused by many classes of
acetylcholine (ACh ... via decreased ACh-mediated ... #differential #diagnosis
Drugs associated with worsening of Myasthenia Gravis (MG):
•	D-penicillamine 
•	Botulinum toxin.
•	Telithromycin
•	Fluoroquinolones 
•	Quinine
•	Magnesium
•	Macrolide antibiotics 
•	Corticosteroids (may cause transient
of generalized AChR-MG ... muscle-specificreceptortyrosinekinase #AChR