11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Pharmacology #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
and DOACs VKA, Dabigatran ... Anticoagulants #DOACs #anticoagulation ... #Switching #hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Protamine sulfate - Dabigatran ... PCC (Kcentra) #anticoagulation ... #pharmacology #hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
patients 5mg bid Dabigatran ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Rivaroxaban #Dabigatran
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
Very Quick Guide to Reversing Antithrombotic Therapy
Aspirin 
Clopidogrel 
Prasugrel 
Ticagrelor 
Abciximab 
Tirofiban 
Eptifibatide 
Unfractionated Heparin 
Low
Bivalirudin Dabigatran ... Antithrombotic #Anticoagulation ... Antiplatelet #Management #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
diagnosis #models #hematology ... pathophysiology #anticoagulation ... anticoagulant #Warfarin #Dabigatran
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy
Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
, Bivalirudin, Dabigatran ... Antithrombotic #anticoagulation ... #agents #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Dabigatran has moderate ... #Chemotherapy #Oncology ... #Hematology #Interactions
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology