7 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
and DOACs VKA, Dabigatran ... Anticoagulants #DOACs #anticoagulation ... #Switching #hematology ... #pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Protamine sulfate - Dabigatran ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
patients 5mg bid Dabigatran ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Rivaroxaban #Dabigatran
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
thrombin #clot #PT #PTT ... diagnosis #models #hematology ... pathophysiology #anticoagulation ... anticoagulant #Warfarin #Dabigatran
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
concentrations of dabigatran ... #doac #noac #anticoagulation ... #hematology #laboratory ... #testing #aptt
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Dabigatran has moderate ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology