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anticoagulation doac anticoagulant diagnosis management noac pathophysiology apixaban bleeding bruising clot coagulation dabigatran differential edoxaban hemostasis inhibitor mechanisms medications models
Coagulation Cascade and Anticoagulant Sites of Action - Amy Chung, MD, MSc https://twitter.com/AmyChung #AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... and Anticoagulant ... #Anticoagulants ... #Medications #Pharmacology ... Mechanisms #DOAC #Hematology
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Anticoagulants Common ... Reversal Agents ... PCC (Kcentra) - Heparin ... anticoagulation #doac #noac #pharmacology ... #hematology #reversal
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... #Coagulation #Cascade ... diagnosis #models #hematology ... anticoagulation #anticoagulant ... Rivaroxaban #Edoxaban #heparin
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... available #DOAC #Reversal ... #hematology #management ... #pharmacology
Standard Heparin Reversal: Protamine < 30 minutes - 1 unit/100 units of heparin 30-60
Standard Heparin ... Reversal: Protamine ... #Reversal #Protamine ... #pharmacology # ... management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
integrity Clotting cascade ... Acquired: • Heparin ... deficiency • Anticoagulants ... deficiency • Anticoagulant ... Differential #Diagnosis #Hematology
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