50 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... children) • Platelets ... extremely low platelet ... #Purpura #Thrombocytopenia ... Diagnosis #Overview #Hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... , Large platelets ... chain IIA • Thrombocytopenia ... fibrinogen) • Thrombocytopenia ... differential #diagnosis #hematology
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
cardiovascular disease ... in setting of thrombocytopenic ... heparin-induced thrombocytopenia ... in idiopathic thrombocytopenic ... von Willebrand disease
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Heparin-Induced Thrombocytopenia ... score: - Thrombocytopenia ... (platelet count ... Timing of onset of platelet ... #HIT #hematology
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Causes of Thrombocytopenia ... Platelet counts ... due to increased platelet ... #Diagnosis #Hematology ... #Thrombocytopenia
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... Gplb receptor • Thrombcytopenia ... Von Willebrand Disease ... #disorders #hematology
Algorithm for diagnosis of familial thrombocytopenia. Platelet size, best determined by review of the peripheral smear,
diagnosis of familial thrombocytopenia ... Platelet size, best ... #Diagnosis #Hematology ... #Familial #Thrombocytopenia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... History: - Prior platelet ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... Causes #Workup #hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... MatthewHoMD #Thrombocytopenia ... Diagnosis #Algorithm #hematology ... #platelets
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... for Causes of Thrombocytopenia ... Spleen L - Liver Disease ... Mnemonic #Acronym #Thrombocytopenia ... Differential #Diagnosis #Hematology