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diagnosis hematology management product reactions anemia aplastic blanching coagulation dic disseminated ecchymosis hematomas intravascular leukemia mds myelodysplasia myelodysplastic petechiae syndromes
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
individuals with thrombocytopenia ... Bruise (also called ... ecchymosis) is caused ... #Bruise #ecchymosis ... #thrombocytopenia
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Treat primary cause ... Coagulation #diagnosis #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... platelet count (thrombocytopenia ... Out Secondary Causes ... IDUS) • Immune Thrombocytopenia ... #oncology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... decrease in most cases ... of Peripheral blood ... Diagnosis #Workup #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... more likely to cause
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... -> AML: Blast crises ... infiltrates (anemia, thrombocytopenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
infections/fevers • Thrombocytopenia ... and petechiae Causes ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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