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Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Insufficiency #AI ... Diagnosis #Algorithm #Causes
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
: Most Common Cause ... Adrenalitis Other causes ... is absent (low ACTH ... Causes of Secondary ... ACTH STIM TEST:
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can cause ... /dL -> Primary AI ... ug/dL Primary AI
Adrenal Crisis Do not confuse acute adrenal crisis with Addison disease. In 1855, Thomas Addison described a
hemorrhage can be a cause ... the most common cause ... the most common cause ... hydrocortisonr #ACTH ... #AI ##adrenals
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Axis Response to ACTH ... primary OR secondary AI ... unclear (often the case ... Measure ACTH: ... Diagnosis #Algorithm #ACTH
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
specificity for AI ... > 15 excludes AI ... - Check ACTH ... have diagnosed AI ... primary vs secondary AI
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
insufficiency (AI ... secondary or tertiary AI ... ACTH, adrenocorticotropic ... Diagnosis #Endo #ACTH
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Pathophysiology Primary AI ... be low, while ACTH ... Secondary AI = the ... Low ACTH leads to
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... , RTA Type IV, AI ... levels, Cortisol+ACTH ... only if no clear cause
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Weakness, fatigue, nausea ... Adrenocorticotropic hormone (ACTH ... Baseline plasma ACTH ... High baseline ACTH ... normal baseline ACTH
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