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Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
specificity for AI ... > 15 excludes AI ... - Check ACTH ... have diagnosed AI ... primary vs secondary AI
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Axis Response to ACTH ... primary OR secondary AI ... Measure ACTH: ... High = primary AI ... Diagnosis #Algorithm #ACTH
Algorithm for the diagnosis of adrenal insufficiency (AI). The standard cosyntropin stimulation test (CST) may be
insufficiency (AI ... secondary or tertiary AI ... ACTH, adrenocorticotropic ... Diagnosis #Endo #ACTH
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
Pathophysiology Primary AI ... be low, while ACTH ... Secondary AI = the ... Low ACTH leads to
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
In secondary AI ... is absent (low ACTH ... diagnostic of AI ... ACTH STIM TEST: ... baseline cortisol and ACTH
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Diagnosis Algorithm ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Insufficiency #AI
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
AM cortisol and ACTH ... /dL -> Primary AI ... present - ACTH ... ug/dL Primary AI ... present - ACTH
Fibrinolysis. Fibrinolysis occurs when plasminogen is activated to plasmin under the influence of factors such as
Plasmin then acts ... and urokinase act ... -antiplasmin), act ... #Plasminogen #Pharmacology
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm Exogenous (ACTH-independent) Endogenous • ACTH-dependent: - ACTH-secreting
Algorithm Exogenous (ACTH-independent ... Endogenous • ACTH-dependent ... : - ACTH-secreting ... Disease) - ACTH-secreting ... in the body • ACTH-independent
Central Nervous System Pharmacology - Somatic and Autonomic Receptors Somatic • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
Nervous System Pharmacology ... the levels of Ach ... and Digest” - Ach ... Adrenal Medulla - Ach ... Autonomic #Receptors #Pharmacology
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