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management differential algorithm approach druginduced joint lupus pain syndrome activation causes damage dermatology disease exposure gap globulin gout igg4 macrophage
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... exam and imaging Treatment ... ideally limit for acute ... Leflunomide (LEF) • JAKi ... #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
: • Acute or chronic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
lesions, meninges, kidneys ... with response to treatment ... hypergammaglobulinemia, ↑ acute ... management #phenotypes #workup ... #treatment #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... myalgia, serositis, Kidney ... • Immunologic Workup ... #rheumatology # ... diagnosis #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Heart, lung, and kidney ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... oxygen sensing (at kidneys ... you’ll do a good workup ... #Algorithm #workup ... #hematology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Gout - Diagnosis ... frequent attacks • Arthritis ... Dual-energy CT → MSU ... gout treatment; ... #rheumatology
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