17 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Workup Blood Work ... Fractional excretion of Cl ... dr_missyhanna #Gitelman ... #Workup #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
- Differential Diagnosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Differential #Diagnosis ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
- Differential Diagnosis ... Bartter Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Differential #Diagnosis ... #Algorithm #Nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
diarrhea / IBD Renal ... syndromes - Gitelman ... #Differential #Diagnosis ... Low #Magnesium #Table ... Classification #Causes #Workup
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... mOsm/kg - Implies renal ... Hypervolemic (Excess salt ... #nephrology #sodium
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
- Differential Diagnosis ... Framework and Workup ... (GFR 20-50 ml/min ... #Differential #Diagnosis ... #Workup #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
AR) hypokalemic salt-losing ... • Hypokalemia (renal ... Sjögren syndrome, Renal ... #Syndrome #diagnosis ... #nephrology #management
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
≥100): SIADH, Renal ... Insufficiency, Cerebral Salt ... #differential #diagnosis ... #table #sodium ... #nephrology
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hyperaldosteronism, Salt ... Hypodipsia - Renal ... Classification #Features #Diagnosis ... #Comparison #Table ... #Nephrology