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management differential symptoms nephrology hepatology treatment algorithm complications endocrinology gitelman lfts abnormal acromegaly acute alkphos ammonia bilirubin bulimianervosa causes checklist
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
and Bilirubin Metabolism ... insult Bilirubin metabolism ... #ASTALT #AlkPhos ... Bilirubin #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
manifestations of acute liver ... abnormalities Liver ... : Loss of metabolic ... #failure #Signs ... #Symptoms #Diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Pancreatitis - Elevated Liver ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
glucose, fluid, salt ... • Incr Glucose Metabolism ... - Metabolic ... #diagnosis #pathophysiology ... #symptoms #signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone: • Liver ... activates JAK-STAT ... activates lipolysis Signs ... thickness) - metabolic ... endocrinology #pathophysiology
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... cycle found in the liver ... concentrations > 5 μg/mL ... Diagnosis of MALA ... Toxicity #Toxicology #Diagnosis
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... autosomal recessive salt-losing ... → Hypokalemia Metabolic ... #Pathophysiology ... #nephrology #diagnosis
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... and decreased metabolism ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Problem Representation An evolving summary of a patient’s clinical presentation that strives to identify (1) Clinical syndrome
(1) Clinical syndrome ... (signs/symptoms ... pattern to maximize diagnostic ... • One-liner at start ... Representation #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... • Metabolic/Hereditary ... be abnormal AST ... • Gilbert's syndrome
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