3 results
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Antiarrhythmics ... depolarization in fast AP ... depolarization in slow AP ... depolarization in slow AP ... #Classes #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
blocking effects and AP ... Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... Action, ←→ EFR & AP ... phase 2 (↑ERP & ↑AP
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
blocking effects and AP ... Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... Action, ←→ EFR & AP ... phase 2 (↑ERP & ↑AP