3665 results
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
phos/ULN ALP) ... Cholestasis • ALP ... disease • If ALP ... both are normal - ALP ... • Elevation of ALP
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... • Severe - ALT ... • Moderate - ALT ... Cholestatic Pattern (ALP ... > ALT or AST):
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
kidney, brain ALT ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... / ULN ALP)
Natriuretic Peptides - Pathophysiology
 • Brain Natriuretic Peptide (BNP)
 • Atrial Natriuretic Peptide (ANP)
 • N-terminal
Natriuretic Peptides - Pathophysiology ... Natriuretic Peptide (ANP ... BNP #NTproBNP #ANP ... #cardiology #Pathophysiology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... Findings: • ↑AST/ALT ... , ↑Tbili/Dbili/AP ... diagnosis #management #pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
specificity to elevated ALP ... • AST/ALT > ALP ... GGT/5-NT: ↑ - ALP ... disease - If ALP ... hemolysis) • ALP
The cardiac cycle and the ECG, all together explained

#Pathophysiology #Cardiology #CardiacCycle #Stages #Systole #Diastole #HeardSounds #Pressures
cycle and the ECG, all ... explained #Pathophysiology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Chemistry Tests - AST, ALT ... Metabolism AST and ALT ... cytoplasmic (CAST) • ALT ... clearance - AP ... Bilirubin #Hepatology #Pathophysiology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Diagnostic Algorithm Pathophysiology ... : - Catch-all term ... range of potential pathophysiologic ... - Pathophysiology
Heme Synthesis Pathway
Enzymes
1. ALA Synthase
2. ALA Dehydratase
3. Porphobilinogen deaminase
4. UP Ill Synthase
5. UP Ill Decarboxylase
6. Coproporphyrinogen
ALA Synthase 2. ... ALA Dehydratase ... Synthesis #Pathway #pathophysiology