77 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... suspicion of severe disease ... splenomegaly, abnormal neurology ... - Sickle cell disease ... Peds #Pediatrics #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... PT, aPTT(liver disease ... (CVID, WAS), (neurologic ... /psychiatric changes ... not required in all
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... , PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... disease progresses ... Differential Diagnosis ... , IgG4 related disease ... #workup #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... Diagnosis - If suspected ... , AIH diagnosis ... Hepatitis (eg Viral) Management ... #Management #Hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : - Neuro: AMS ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
adult population: also ... Malnutrition • Wilson's disease ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Findings: • ↑AST/ALT ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Medium and large also ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... and Management ... decreased reflexes Pathophysiology ... should be done in ALL ... CMC_IM #Potts #Disease