15 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
and Primary Causes ... Liver Function Tests ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... • Nephrotic syndrome ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Classified among the secondary ... Liver function tests ... Diagnosis #Management #Hematology ... #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Demyelinating Syndrome ... autoantibodies that will cause ... APS), Secondary ... CNS #neurology #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... Type III Often Secondary ... diagnosis #types #classification
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
into a 4-pass system ... pass = Dangerous secondary ... Chronic & Rx-related Secondary ... cell activation syndrome ... Mastocytosis • Other hematologic
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Secondary form associated ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Liver Function Tests ... Myelodisplastic syndrome ... #Pruritus #secondary ... #systemic #generalized ... Diagnosis #Algorithm #causes
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... frequently affected systems ... Better call hematology ... causes: Many of ... Best to have an
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... • Cogan Syndrome ... retinopathy Lab Tests ... differential #diagnosis #rheumatology ... #classification