12 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... anemia) Labs ... of CD34+ cells is ... anemia Treatment ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
WORKUP & DIAGNOSIS Labs ... confirm DAH, r/o infection ... sparing of the lung ... diagnosis #management ... #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Diagnosis: • Labs ... Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... APML #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis is ... life-threatening Differential ... Labs: - AchR antibodies ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
organizing pneumonia, ARDS ... respiratory distress syndrome ... failure - Infectious ... Labs: • Nonspecific ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... • HLH Labs: ... Treatment: • Corticosteroids ... #Diagnosis #Management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... lab markers such ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Hemolysis on labs ... Related Acute Lung ... TRALI resembles ARDS ... due to marrow aplasia ... Transfusion #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Ocular examination Labs ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management