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diagnosis treatment erythematosus hemophagocytic hlh lupus lymphohistiocytosis sle systemic adult aosd cerebritis cns disease encephalopathy hepatic hepatology hodgkins lymphoma macrophage
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... nervous system (CNS) dysfunction ... Histopathologic criteria ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Encephalopathy, Cognitive Dysfunction ... inflammation, leading ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... genetic immune dysfunction ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
5 of the below criteria ... Minor criteria include ... splenomegaly, liver dysfunction ... AOSD #diagnosis #rheumatology ... #management
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
Diagnosis and Management ... TIPS West Haven Criteria ... Encephalopathy #Grading ... #Classification ... #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Non-autoimmune rheumatologic ... mild cognitive dysfunction ... Chronic B-cell activation ... Erythematosus #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... through Ann Arbor criteria ... lymphoma #diagnosis #classification ... #hematology #oncology ... #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
and fatigue Criteria ... insufficiency • Cognitive dysfunction ... Polychondritis #rheumatology ... #diagnosis #management
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