47 results
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Must Be On" • ACEI ... , ARB, or ARNI AND ... Reducing: • ACEI ... or ARB • ARNI ... #medications #chf
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Stepwise Approach: ACE ... , ARB, ARNI → Beta-Blocker ... -2 Inhibitor → ARNI ... Heart #Failure #CHF
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Beta-blocker • ACE ... , ARB, ARNI • ... Heart #Failure #CHF
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
AngiotensinReceptorNeprilysinInhibitor #ACEi ... angiotensinreceptorblockers #ARB #ARNI ... #PARADIGM-HF #EMPEROR-Reduced
Target Doses in Congestive Heart Failure
 • Beta Blockers: Bisoprolol, Carvedilol, Metoprolol succinate, ARNI, Sacubitril/valsartan
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Metoprolol succinate, ARNI ... Sacubitril/valsartan • ACEI ... #HeartFailure #CHF
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
development of HF ... and recommended ... ACEI indicates angiotensin-converting ... circulatory support; and ... #CHF #Congestive
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
initiate them on ACEI ... maximally tolerated ACEI ... Entresto (replacing ACEI ... spironolactone, and ... /ambcarerx #CHF
Lumbar Central Canal Stenosis Grading 
  - Normal - No CSF effacement 
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- Normal - No CSF ... effacement of CSF ... effacement of CSF ... and sac deformity ... Diagnosis #Radiology #MSK
ACEi/ARBs in COVID-19: Beneficial, Bad, or Benign?
Preclinical studies suggest ACEi/ARB use increases ACE2 expression, raising concern
ACEi/ARBs in COVID ... studies suggest ACEi ... David Rink, MS4 ... @de_Rink and Kerryn ... Roome, MS4 @KerrynRoome
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
81% for acute HF ... 5 pts w/ acute HF ... Pharmacology: • ACE ... ARBs • ARNIs ( ... #pharmacology #sCHF