24 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... , AKI, acute limb ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
bladder and rectal reflex ... Injury #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... Findings: • ↑AST/ALT ... #management #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Tuberculosis - Diagnosis ... and Management ... numbness, decreased reflexes ... Pathophysiology ... should be done in ALL
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... - Symptoms of ... Anti-LKM & Anti-ALC ... Hepatitis (eg Viral) Management ... #Management #Hepatology
Esophageal Variceal Bleeding - Scoping Summary
GENERAL PRINCIPLES OF MANAGEMENT (VARICEAL-B):
V - Vasoconstrictor therapy: (Octreotide 50mcg bolus
PRINCIPLES OF MANAGEMENT ... acquired/vasoactive meds ... Fibrinogen >120 refer ... not initiate in acute ... Summary #Endoscopy #diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... gastrointestinal distress and acute ... Clinical presentation also ... includes symptoms ... #Management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Rare: DAH, acute ... : >3 symptoms, or ... , Anaphylaxis, Acute ... #management #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Increased Jaw Jerk reflex ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology ... #diagnosis #management
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Syndrome - Summary Acute ... Guillain-Barre Pathophysiology ... Decreased / Absent Reflexes ... #management #treatment ... #neurology