12 results
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... • Native and ... Sources #Causes ... #Bacteria #Etiology ... #Differential #
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
culture negative ... infective endocarditis ... under BCNIE, these bacteria ... #differential # ... #Endocarditis #
Differential Diagnosis for Concurrent Brain and Lung Infections
 • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Differential Diagnosis ... for Concurrent ... • Bacteria: Strep ... phenomena from endocarditis ... Diagnosis #causes
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
Differentiating NBTE from Infective ... Features of Non-Bacterial ... valves • MRI brain ... in up to 30% of cases ... often seen • MRI brain
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... Lung Lesions • Bacteria ... phenomena from endocarditis ... #Differential # ... Diagnosis #causes
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... Lung Lesions • Bacteria ... phenomena from endocarditis ... #Differential # ... Diagnosis #causes
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... Infective Endocarditis ... but important causes ... #Infective #Endocarditis ... #diagnosis #differential
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Fever Patterns - Differential ... • Typhus, gram-negative ... Pyogenic/focal infection ... Non-Infectious Causes ... Fever #Patterns #Differential
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
children Common bacterial ... causes in children ... • Enteric gram negative ... artery (e.g., endocarditis ... in those with concurrent
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Coagulase-negative ... Septic Emboli Cause ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... • Persistent bacteremia