4 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Infective Endocarditis ... but important causes ... #BloodCulture # ... #Endocarditis # ... diagnosis #differential
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Coagulase-negative ... Septic Emboli Cause ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... Treat underlying cause
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
Common bacterial causes ... • Enteric gram negative ... artery (e.g., endocarditis ... in those with concurrent ... children #peds #differential
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... aureus, Coagulase-negative ... staphylococci Culture Negative ... Septic emboli cause ... #Differential #