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diagnosis algorithm cardiology hemolytic rheumatology agglutinin bandemia causes cbc cold disease erythematosus framework infectiousdiseases lupus management neutrophil nonpalpable palpable pathophysiology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... quinine, etc) - Viral ... - Mechanical: valve ... replacement, endocarditis ... Diagnosis #Framework #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... mountain spotted fever ... • Bacterial endocarditis ... #Diagnosis #hematology ... #nonpalpable #dermatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Leukocytosis, anemia ... Persistent bacteremia/fevers
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... mechanical cardiac valve ... bartonella (oroya fever ... Algorithm #workup #hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential ... involves aortic and mitral ... night sweats, fever ... Leukocytosis, anemia ... #Endocarditis #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Red Flags: • Fever ... Schonlein Purpura - Endocarditis ... Microscopic) - Viral ... Algorithm #Causes #dermatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... appreciate the value ... tachycardia or fever ... #differential # ... neutrophil #WBC #CBC #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... Symptoms: High fevers ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve ... lymphopenia, low PLT • Anemia
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