7 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
negative anti-lgG ... younger pts) Differential ... Symptoms: High fevers ... chills, flank pain ... hemolytic #anemia #hematology
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Ewing sarcoma • Legg-Calve-Perthes ... Pain: • Infection ... /swelling - Fever ... #pain #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... infection • ... infection, Amyloidosis ... conditions #joint #pain ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... • Rheumatic fever ... • Bacterial endocarditis ... #Differential # ... Diagnosis #MSK #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... - Trauma - Infection ... Red Flags: • Fever ... lesions • Severe pain ... Schonlein Purpura - Endocarditis
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... acute rheumatic fever ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... arthralgia, arm/leg ... tract: Abdominal pain ... purpura (lower legs ... infection, drug