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diagnosis hematology joint arthritis blood management product reactions agglutinin anemia approach cold conditions disease erythematosus extrarticular hemolytic lower lupus monoarthritis
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Ewing sarcoma • Legg-Calve-Perthes ... Pain: • Infection ... /swelling - Fever ... #pain #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
infection • ... Cardiovascular system • Mitral ... infection, Amyloidosis ... #differential # ... diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Arthritis Differential ... • Rheumatic fever ... • Bacterial endocarditis ... #Differential # ... Diagnosis #MSK #
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... acute rheumatic fever ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
infection, autoimmune ... negative anti-lgG ... younger pts) Differential ... Symptoms: High fevers ... chills, flank pain
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... arthralgia, arm/leg ... purpura (lower legs ... infection, drug ... #Diagnosis #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint pain ... hypertension, lower extremity ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine ... anaphylactoid (not lgE ... Infection - Infection ... RBCs (stored at 4C ... False negative: Extremely
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine ... • Infection - ... Infection occurs ... RBCs (stored at 4C ... False negative: Extremely
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