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differential management amiodarone associations autoimmune comparison connectivetissuediseases diseases findings induced interstitial lungdisease myopathy myositis pocus signs sjogrens table toxicity toxicology
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... • Idiopathic pulmonary ... Churg Strauss syndrome ... #diagnosis #differential ... #pulmonary #causes
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
disease-associated interstitial lung ... PSS: Sjogren syndrome ... #LungDisease #CTILD ... #Diagnosis #Differential ... #Rheumatology #
Pulmonary Pathology and Associated Lung Ultrasound Findings Pneumothorax: - No lung sliding/barcode sign - Lung point (hard
Ultrasound Findings ... pleura reflection) Pneumonia ... pleura in severe cases ... Respiratory Distress Syndrome ... #differential #diagnosis
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... respiratory distress syndrome ... Exclude other causes ... Exclusion of other ILDs
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Usual interstitial pneumonia ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... #Rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... of aspiration pneumonia ... of aspiration pneumonia ... statins - probably caused
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