12 results
Renal Tubular Acidosis (RTA) Diagnosis and Management
 • Distal (type 1) RTA
 • Proximal (type 2)
Renal Tubular Acidosis ... (RTA) Diagnosis ... 4) RTA #rta #Renal ... #Tubular #Acidosis ... #nephrology #table
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Defects in Kidney Tubule ... distal convoluted tubule ... tubular acidosis ... receptor activity #Tubule ... Defects #Kidney #Nephrology
Proximal Renal Tubular Acidosis (RTA) Ttype 2 Overview

HCO3 reabsorptive failure
Lowering of threshold for HCO3 absorption in
Proximal Renal Tubular ... Acidosis (RTA) ... absorption in proximal tubule ... #Proximal #Diagnosis ... #Management #Nephrology
Renal Tubular Acidosis (RTA) 
Type 1 - Failure of secretion
Type 2 - Bicarbonate wasting
Type 4 -
Renal Tubular Acidosis ... salt diet #Renal ... #Tubular #Acidosis ... #RTA #types #classification ... #nephrology #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... in the distal tubule ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Bartter syndrome, Gitelman ... high in kidney tubular ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... hypokalemia • Renal ... tubular acidosis ... Bartter's syndrome, Gitelman's ... algorithm #causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... • Hypokalemia (renal ... tubular acidosis ... #Syndrome #diagnosis ... #nephrology #management
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
chronic respiratory acidosis ... tubule diuretic ... tubule reabsorptive ... furosemide-like lesion) • Gitelman ... #Causes #nephrology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
- Differential Diagnosis ... tubular acidosis ... sedation, narcotics, CVA ... Interpretation #Diagnosis ... #Summary #Nephrology