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differential causes gitelman management syndrome pathophysiology treatment acidosis algorithm alkalosis aniongap hyperkalemia hypertension indications k nongap potassium rhabdomyolysis secondary urinary
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Kidney ... Cl- outside the kidneys ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology ... #diagnosis
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Non-anion Gap Metabolic ... Chronic progressive kidney ... loads (ammonium chloride ... #differential #diagnosis ... #causes #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Work: - Hypokalemia ... Hypomagnesemia - Metabolic ... autosomal dominant kidney ... of echogenic kidneys ... #Workup #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Gitelman #Syndrome #diagnosis ... #nephrology #management
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... with previously stable ... disturbance, or acute kidney ... and metabolic alkalosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Heat stroke - Metabolic ... nephrotoxicity to kidney ... per day until stable ... causes #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... reabsorption) Workup ... Elimination (see Table ... Calcium 2-3g IV Ca-gluconate ... Treatment #potassium #nephrology
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