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differential hypernatremia hypokalemia pathophysiology treatment 1 2 3 alkalosis bartter chloride defects di epithelial hyponatremia inherited insipidus kidney metabolic person
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... Chloride • Urine Ca ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... in the distal tubule ... Contraction → ↑ Renin ↑ Ca ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Stroke Evaluation and Management Algorithm Clinical suspicion of stroke (BE FAST) • Balance loss • Eyes: vision
Algorithm Clinical ... Immediate Workup ... #Algorithm #diagnosis ... #differential #neurology ... #CVA
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup Step #1 - Consider the history Step #2 - Assess
Hypernatremia Differential Diagnosis ... Insipidus Workup ... Hypernatremia #Management ... #Algorithm #Sodium ... #nephrology #insipidus
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... , Cushing syndrome ... #Workup #Algorithm ... #nephrology #sodium
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
and Workup Step ... Repeat the sodium ... • nephrotic syndrome ... #Workup #Algorithm ... #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... distal convoluted tubule ... #Syndrome #diagnosis ... #nephrology #management
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... , Gitelman syndrome ... in the proximal tubule ... #nephrology #differential ... #diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and Management ... antibody that works ... others (botox, sodium ... #Management #treatment ... #neurology
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