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differential algorithm metabolic hypokalemia syndrome causes pathophysiology chloride potassium defects epithelial framework hypochloremia hypophosphatemia inherited low management phosphate primary table
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
syndrome • Urine ... Chloride • Urine ... Ca/Cr ratio ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic Alkalosis ... - Differential Diagnosis ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... #Algorithm #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
diuretic use, Bartter ... syndrome, Gitelman ... in the proximal tubule ... #Algorithm #nephrology ... #differential #diagnosis
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic Alkalosis ... - Differential Diagnosis ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... #Algorithm #Nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Hypomagnesemia - Metabolic Alkalosis ... Elevated Renin Urine ... of echogenic kidneys ... #Workup #nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... Hypokalemia Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
: Differential Diagnosis ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... #Differential #Diagnosis ... #Causes #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects in Kidney ... acid transporter Bartter ... ascending limb Gitelman ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... - Metabolic Alkalosis ... syndrome, Gitelman ... #Hypokalemia #diagnosis ... differential #potassium #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
distal convoluted tubule ... Hypocalciuria (spot urine ... syndrome • Pseudo Bartter-Gitelman ... #Syndrome #diagnosis ... #nephrology #management
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