11 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Differentiating Gitelman ... syndrome from Bartter ... Chloride • Urine Ca ... #Algorithm #nephrology ... #hypokalemia #diagnosis
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
How do you work ... hemorrhage and other mimics ... suspicion) • +/- bubble ... #diagnosis #checklist ... #neurology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... acid transporter Bartter ... ascending limb Gitelman ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... in the distal tubule ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... autosomal dominant kidney ... of echogenic kidneys ... dr_missyhanna #Gitelman ... #Workup #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter ... syndrome, Gitelman ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... #Hypokalemia #diagnosis ... differential #potassium #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
↑ Aldosterone: Kidney ... Mg2+ deficiency, Bartter ... syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... Refeeding syndrome • Bartter ... syndrome • Pseudo Bartter-Gitelman ... #Syndrome #diagnosis ... #nephrology #management
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
: Differential Diagnosis ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... #Differential #Diagnosis ... #Causes #nephrology