8 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... acid transporter Bartter ... ascending limb Gitelman ... #Nephrology #Diagnosis ... #Differential #
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
How do you work ... hemorrhage and other mimics ... suspicion) • +/- bubble ... #diagnosis #checklist ... #neurology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter ... syndrome, Gitelman ... urine #Algorithm #nephrology ... #differential # ... diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... #Hypokalemia #diagnosis ... #potassium #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
↑ Aldosterone: Kidney ... Mg2+ deficiency, Bartter ... syndrome, Gitelman ... #algorithm #diagnosis ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... ratio 0.5%) Differential ... syndrome • Pseudo Bartter-Gitelman ... #Syndrome #diagnosis ... #nephrology #management
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Metabolic Alkalosis: Differential ... Diagnosis ECF ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Osmotic diuresis, Bartter's ... syndrome (mimics ... diuretic use), Gitelman's ... Hypokalemia #Causes #differential ... #diagnosis #nephrology