9 results
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Workup for Hypophosphatemia ... - Differential Diagnosis ... Glucose, Acute resp. alkalosis ... , CA Inh., Osmotic ... #phosphate #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... Workup Algorithm ... • Euvolemic (Low ... , Cushing syndrome ... #nephrology #sodium
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
How do you work ... suspicion) • +/- bubble ... #stroke #workup ... #diagnosis #checklist ... #neurology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
- Differential Diagnosis ... Appropriately Low ... Acute Respiratory Alkalosis ... #Algorithm #nephrology ... #phosphorus #workup
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... Hypokalemia Metabolic alkalosis ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
• Normal/low ... , Gitelman syndrome ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
- Differential Diagnosis ... D-lactate (short bowel syndrome ... sedation, narcotics, CVA ... #Summary #Nephrology ... #ABG #bloodgas
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... hypomagnesemia • Metabolic alkalosis ... • Normal or low ... Hypochloremic metabolic alkalosis ... #diagnosis #nephrology
Citrate Anticoagulation Toxicity

Hypernatremia (HyperNa):
 - Citrate solutions may have ↑ sodium content and should be paired
Anticoagulation Toxicity Hypernatremia ... dysfunction or low ... metabolism Metabolic alkalosis ... Toxicity #toxicology #nephrology ... #diagnosis